Among the handful of pre-1930 commemorative half dollars is the 1926 United States Sesquicentennial, commemorating the 150th anniversary of the signing of the Declaration of Independence. This coin was struck in large numbers of over 1 million pieces and sold for $1 apiece, but most were melted. The 1926 Sesqui was designed by John Frederick Lewis and on its obverse features a jugate obverse portrait of first United States President George Washington and contemporary Commander-in-Chief Calvin Coolidge; the reverse showcases the Liberty Bell.

Like many of the earlier commemoratives, the 1926 Sesquicentennial half dollar was not widely saved in the higher grades, and many entered circulation. Most 1926 Sesquis are encountered in grades of MS62-64, with few grading MS65 or MS66. Any pieces grading higher are extremely rare. Be careful when buying 1926 Sesquis sight-unseen, as many pieces exhibit unsightly yellow toning.